Looking for a natural, effective way to manage your appetite without turning to restrictive diets? Meet Amarasate – a clinically proven, plant-based extract that's changing the game in appetite management.
But what exactly is Amarasate, and why is it the hero ingredient behind Calocurb, a supplement designed to support healthy eating habits? Let's break it down.
From Hops to Hunger Control
You might know hops as a key ingredient in beer, or their long-held place in herbal medicine for their calming and digestive benefits. Now, modern science has uncovered a powerful new use for a particular type of hop and its flower extract: appetite regulation.
After screening more than 900 bitter plants during years of research searching for a natural weight management solution, a team of New Zealand scientists at Plant & Food Research — and in 2014, they found it. A little-known New Zealand hop flower extract was identified as containing bitter compounds capable of activating a feeling of fullness in the body, and Amarasate was born. What makes it special is its ability to activate something called the "bitter brake" — a natural biological mechanism that helps the body manage hunger and promote feelings of fullness in response to eating bitter substances.
How Amarasate Works with Your Body
Amarasate is unique. Through the super-stimulation of the bitter taste receptors in the small and large intestines, Amarasate activates three key satiety hormones: GLP-1 (glucagon-like peptide-1), CCK (cholecystokinin), and PYY (peptide tyrosine tyrosine). This stimulation connects to the brain and reduces cravings by 40%, hunger by 30%, and calorie intake by 18%.1,2
Here's how it helps curb appetite in a natural, science-backed way:
Activates Bitter Taste Receptors in the Gut
Your digestive system is equipped with bitter taste receptors (TAS2Rs) – yes, beyond your tongue! These receptors respond to bitter compounds found in plants like hops and some leafy greens. When Amarasate is released in the upper small intestine, it stimulates TAS2Rs on special enteroendocrine cells there and all down the length of the gut, whose job is to sense the chemical makeup of food. Some of these cells are primed to respond to bitterness, so in response to that stimulation, they release GLP-1, CCK, and PYY.
Triggers Satiety Hormones
When activated by Amarasate's bitter compounds, these cells release satiety hormones that signal the body to stop eating:
- GLP-1: Slows stomach emptying and increases the feeling of fullness.
- PYY: Helps reduce hunger and supports portion control.
- CCK: Slows stomach emptying and raises leptin (another hormone that increases satiety).
Sends a "Stop Eating" Signal to the Brain
The satiety hormones released trigger a feeling of fullness and slow down stomach emptying. Scientists call this stop-eating signal "the bitter brake" — catchy, isn't it? So Amarasate helps you feel satisfied sooner and for longer.
Why Does Bitterness Trigger Fullness?
This response to bitterness is thought to be an evolutionary mechanism designed to help early humans steer clear of potentially dangerous foods, which were often bitter. Think of it as a second line of defence — after taste — against toxic plants, which are often bitter-tasting. Calocurb mimics this natural response to bitterness — without the danger — making it a powerful tool for cutting calorie intake at meals and snacks.
The Science of Delivery: How Amarasate Reaches the Right Place
The bitter brake works best when the bitter compounds are delivered to the part of the gut with the most enteroendocrine cells — the stomach and the lower small intestine.3 However, activation of stomach TAS2Rs can be associated with nausea, vomiting, and even an increase in ghrelin, the major start eating" hormone. (That makes sense from the evolutionary perspective, to help dilute whatever the bitter — potentially toxic — substance might be and also to expel it from the stomach.) So it's important that the Amarasate gets beyond the stomach to the target cells in the small intestine and beyond.
Normal pharmaceutical capsules break down in the stomach, but Calocurb's delayed-release capsule is engineered to dissolve in the duodenum, activating the stop-eating signal and triggering fullness within an hour. Once released from the Calocurb capsule, the Amarasate doesn't dissolve and isn't absorbed; rather, it continues down the length of the gut, activating TAS2Rs all the way, so its effect lasts up to 4 hours. This combination of advanced capsule technology and the bitter brake breakthrough is what makes Calocurb effective.
Amarasate vs. Synthetic Appetite Suppressants
Many appetite control solutions rely on synthetic ingredients or stimulants that can lead to unwanted side effects. Here's how Amarasate compares:
| Feature | Synthetic Appetite Suppressants | Amarasate |
|---|---|---|
| Source | Synthetic / Lab-created | Natural / Derived from hops |
| Mechanism | Super-stimulate "stop eating" hormone receptors and/or alter brain chemistry | Works through gut signalling |
| Side effects | Gastrointestinal side effects common (especially with GLP-1 mimics); jittery side effects with stimulants | Temporary laxative effect in less than 10% of users when they start Amarasate |
| Ingredient type | Synthetic ingredients or stimulants | Plant-based |
| Hunger regulation | Overrides natural hunger signals | Supports body's own hunger-regulation processes |
With growing awareness around bitter compounds and their role in appetite control, Amarasate is gaining recognition as an innovative, plant-based way to manage hunger — without overriding your body's natural signals.
Why Amarasate Powers Calocurb
Calocurb is the only supplement on the market that contains this patented Amarasate formula. It's a unique, clinically studied solution that fits into a busy lifestyle — offering appetite support you can feel good about.
Each Calocurb capsule contains just three natural ingredients:
- 125 mg of Amarasate hop extract
- Rosemary extract
- Vegetable oil
That's it. No fillers, stimulants, or synthetic additives.
Key Benefits of Amarasate in Calocurb
Here's what you can expect when using Calocurb:
- Feel full sooner and for longer — Natural satiety helps prevent overeating.
- Curb unnecessary snacking — Support a balanced appetite throughout the day.
- Healthy weight management — Stay in tune with your body's natural hunger cues.
- Avoid harsh ingredients — A plant-powered alternative to traditional appetite suppressants.
Natural appetite control
The only supplement with patented Amarasate®
Three natural ingredients. Clinically tested. No fillers, stimulants, or synthetic additives. Calocurb works with your body's own biology to help you feel full sooner and for longer.
The Future of Appetite Control Starts with Nature
Amarasate represents a shift toward science-backed, natural solutions for appetite and weight management. Its effectiveness lies in working with your body — not against it.
If you're looking for a supplement that helps you stay in control of your eating habits — without extremes — Calocurb, powered by Amarasate, may be exactly what you've been searching for.
