5 Impressive Health Benefits of Hops

Hops are more than a brewing ingredient — their bitter compounds and phytoestrogens have attracted serious scientific interest for weight, mood, and more.

5 Impressive Health Benefits of Hops

Key Takeaways

  • Bitter compounds in hops may activate gut receptors that release appetite-regulating hormones, helping reduce hunger and support weight management.
  • Hops contain potent plant-derived phytoestrogens that early research suggests may help relieve some menopause symptoms.
  • Laboratory and small human studies indicate hops compounds may support healthy blood vessel function and cardiovascular health.
  • Hops extracts have shown potential to improve feelings of stress, anxiety and mild depressive symptoms in small clinical trials.
  • Polyphenols and bitter acids in hops have demonstrated anti-inflammatory activity, though most evidence currently comes from lab and animal studies.

Hops (Humulus lupulus) are the flowering cones of the hop plant, best known for giving beer its distinctive bitter flavour and aroma.

Although hops are commonly associated with brewing, they have been used in traditional herbal medicine for centuries and contain a range of naturally occurring bioactive compounds, including bitter acids and polyphenols, that have attracted scientific interest.12

Potential Health Benefits of Hops

1. May help support weight management

One of the most well-researched health benefits of hops is their potential role in appetite regulation.

Clinical studies using a bitter hops extract have shown that consuming the extract before meals can significantly reduce feelings of hunger and decrease energy intake compared with a placebo.3

Researchers believe the bitter compounds in hops activate bitter taste receptors in the gut, stimulating the release of appetite-regulating hormones including GLP-1, CCK and peptide YY, which help promote feelings of fullness.3

Additional human studies have also reported reductions in body weight, body fat and abdominal fat following supplementation with matured hop bitter acids, although more long-term research is still needed.453

Summary

Bitter compounds found in hops may help regulate appetite and support healthy weight management.

2. May help relieve menopause symptoms

Menopause commonly causes symptoms such as hot flushes, sleep disturbances, mood changes and vaginal dryness due to declining oestrogen levels.6

Hops naturally contain phytoestrogens, particularly 8-prenylnaringenin, one of the most potent plant-derived phytoestrogens identified to date. Several small clinical studies suggest hops extracts may help reduce menopausal symptoms, although larger trials are needed to confirm these findings.782

Summary

Early research suggests hops extracts may help relieve some menopause symptoms, although further high-quality research is needed.

3. May support cardiovascular health

Cardiovascular disease remains the leading cause of death worldwide.9

Laboratory and small human studies suggest compounds found in hops may improve blood vessel function by supporting healthy endothelial function and vascular relaxation. However, more clinical studies are needed before firm conclusions can be drawn.1011

Summary

Emerging research suggests hops may support healthy blood vessel function, although evidence in humans remains limited.

4. May support mood and wellbeing

Several compounds found in hops, including humulones and lupulones, have demonstrated calming properties in laboratory and animal studies.2

Small human studies have also found that hops supplementation may improve feelings of stress, anxiety and mild depressive symptoms compared with placebo, although larger clinical trials are needed.1213

Summary

Early research suggests hops may support mood and relaxation, but more research is required.

5. May help reduce inflammation

Inflammation is a normal part of the body's immune response. However, persistent low-grade inflammation has been linked with chronic diseases including cardiovascular disease, type 2 diabetes and certain cancers.14

Hops are rich in polyphenols and bitter acids that have demonstrated anti-inflammatory activity in laboratory and animal studies by reducing inflammatory signalling molecules such as TNF-α and IL-6.102

While these findings are encouraging, additional human clinical trials are needed to determine whether these effects translate into meaningful health benefits.

Summary

Hops contain naturally occurring compounds with anti-inflammatory properties, although much of the current evidence comes from laboratory and animal research.

References

  1. Aghamiri, V., Mirghafourvand, M., Mohammad-Alizadeh-Charandabi, S., & Nazemiyeh, H. (2016). The effect of hop (Humulus lupulus L.) on menopausal hot flashes: A randomized controlled trial. Complementary Therapies in Clinical Practice, 23, 130–135.
  2. Erkkola, R., Myllymäki, O., & Franke, A. A. (2010). A pilot study of a standardized hops extract in the treatment of menopausal discomforts. Phytomedicine, 17(6), 389–396.
  3. Franco, L., Sánchez, C., Bravo, R., et al. (2012). The sedative effects of a hops extract in healthy adults. Phytomedicine, 19(14), 1347–1352.
  4. Furman, D., Campisi, J., Verdin, E., et al. (2019). Chronic inflammation in the etiology of disease across the life span. Nature Medicine, 25(12), 1822–1832.
  5. Hall, W. L., Formanuik, N. L., Harnpanich, D., et al. (2018). A meal enriched with hops-derived polyphenols improves vascular function. Molecular Nutrition & Food Research, 62(24).
  6. Karabin, M., Hudcova, T., Jelinek, L., & Dostalek, P. (2015). Biologically active compounds from hops and prospects for their use. Comprehensive Reviews in Food Science and Food Safety, 14(5), 542–567.
  7. Kyrou, I., Christou, A., Panagiotakos, D., et al. (2017). Effects of a hops extract on depression, anxiety and stress in healthy adults: A randomized placebo-controlled study. Hormones, 16(2), 171–180.
  8. Morimoto-Kobayashi, Y., Ohara, K., Takahashi, C., et al. (2016). Matured hop bitter acids improve abdominal visceral fat obesity in overweight humans. Nutrition Journal, 15, 25.
  9. Stevens, J. F., & Page, J. E. (2004). Xanthohumol and related prenylflavonoids from hops. Phytochemistry, 65(10), 1317–1330.
  10. Sumiyoshi, M., & Kimura, Y. (2013). Hop bitter acids suppress body fat accumulation in experimental models. Journal of Oleo Science, 62(8), 585–592.
  11. The North American Menopause Society. (2023). The 2023 Nonhormone Therapy Position Statement.
  12. Walker, N., Rea, S., Panahi, S., et al. (2019). A bitter hops extract reduces hunger during intermittent fasting through gut peptide secretion. Nutrients, 11(11), 2754.
  13. World Health Organization. (2023). Cardiovascular diseases (CVDs). https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds)
  14. Zanoli, P., & Zavatti, M. (2008). Pharmacognostic and pharmacological profile of Humulus lupulus L. Journal of Ethnopharmacology, 116(3), 383–396.
Calocurb

Written by

Calocurb

← Back to blog