Injectables releasing GLP-1 (glucagon-like peptide one) synthetics such as Wegovy and Ozempic are making headlines around the world as "miracle" weight-loss drugs, but we are increasingly hearing stories about the resulting negative side-effects and people who regain all the weight and more if they stop. These drugs are so in-demand that diabetes patients who really require this medication are not able to get their hands on it. The main question we get asked is — how does Calocurb compare?
The secret behind current weight-loss drugs is an injectable active ingredient which belongs to a group of GLP-1 receptor agonists. They work by mimicking the naturally occurring GLP-1 hormone; this is not the same as being a natural alternative to the human production of GLP-1.
GLP-1 is released in the gut after meals or when bitter receptors below your stomach are activated. The hormone acts on the pancreas to increase insulin secretion and decrease glucagon secretion (glucagon stimulates sugar production) in response to food, keeping blood sugar from rising too high. GLP-1 also slows down the rate of food leaving the stomach and into the small intestine, and sends signals to your brain's reward centre, decreasing appetite and cravings for food. Once the active ingredient in Calocurb, Amarasate®, is released into the small intestine, it triggers a natural signal for stimulating natural GLP-1 release from specialised cells.
The long-term consequences of using injectables such as Wegovy and Ozempic are not yet known, they're expensive, and recent research has found that two thirds of all people using these injectables rapidly regain the weight they lost during the first year after stopping the medication.1
Maintaining weight loss after losing it is the difficult part — one in which the injectables do not offer an effective solution unless you are willing to inject yourself weekly. The overall evidence-based answer states that while people lose weight while taking an injectable in a dose-dependent and duration-dependent manner, they will tend to regain weight after medication is stopped. Calocurb is the only 100% completely natural and scientifically proven way to reduce caloric intake by 20% and up to a 100% reduction in increased hunger and craving in both men and women.
